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KMID : 1103720150720010011
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Journal of the Korean Society of Radiology
2015 Volume.72 No. 1 p.11 ~ p.19
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Comparison of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography, Hydro-Stomach Computed Tomography, and Their Combination for Detecting Primary Gastric Cancer
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Jeon Gyeong-Sik
Chung Woo-Suk
Song E-Rang
Kim Jin-Suk
Shin Byung-Seok
Ohm Joon-Young
Ahn Moon-Sang
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Abstract
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Purpose: To retrospectively compare the diagnostic accuracy for detecting primary gastric cancer on positron emission tomography/computed tomography (PET/CT) and hydro-stomach CT (S-CT) and determine whether the combination of the two techniques improves diagnostic performance.
Materials and Methods: A total of 253 patients with pathologically proven primary gastric cancer underwent PET/CT and S-CT for the preoperative evaluation. Two radiologists independently reviewed the three sets (PET/CT set, S-CT set, and the combined set) of PET/CT and S-CT in a random order. They graded the likelihood for the presence of primary gastric cancer based on a 4-point scale. The diagnostic accuracy of the PET/CT set, the S-CT set, and the combined set were determined by the area under the alternative-free receiver operating characteristic curve, and sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated.
Results: Diagnostic accuracy, sensitivity, and NPV for detecting all gastric cancers and early gastric cancers (EGCs) were significantly higher with the combined set than those with the PET/CT and S-CT sets. Specificity and PPV were significantly higher with the PET/CT set than those with the combined and S-CT set for detecting all gastric cancers and EGCs.
Conclusion: The combination of PET/CT and S-CT is more accurate than S-CT alone, particularly for detecting EGCs.
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KEYWORD
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Gastric Cancer, Stomach CT, 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography, Detection, Combination
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